Tuesday, March 8, 2011

Face of Panda sign in Wilson's disease

Brain MRI showed bilateral T2 hyperintensity involving putamen, thalami, and brainstem. The midbrain “panda sign” is due to high signal in the tegmentum, normal signals in the red nuclei and lateral portion of the pars reticulata of the substantia nigra, and hypointensity of the superior colliculus.

Dina A. Jacobs, Clyde E. Markowitz, David S. Liebeskind, et al. Neurology 2003;61;969

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