Wednesday, January 8, 2014

Cefepime-induced triphasics


This is the EEG of a patient on cefepime with AKI who got an EEG due to altered mental status and occasional myoclonus.  If you're not aware of this effect (ceftazidime does it too), then you ought to read up.  Not all that uncommon neurotoxicities include: temporospatial disorientation [96%], myoclonus [33%], and seizures [13%].
Nonetheless, this is a beautiful demonstration of triphasic waves: notice the three phases marked by the red-blue-red outlining, and the fact that they tend to march forward in time from frontal EEG leads to more posterior leads (if you don't have a purple line like the above, feel free to fold over your test booklet page).

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